Melanotan II 10mg

Melanotan II 10mg is a synthetic cyclic α-MSH analog research peptide supplied at 99.3% HPLC-verified purity with a full third-party Certificate of Analysis (COA). It is manufactured for laboratory research into melanocortin receptor pharmacology, pigmentation pathways, and energy homeostasis. For laboratory and research use only. Not for human consumption.

At a Glance

• Compound: Melanotan II (Melanotan II Acetate) — CAS 121062-08-6
• Purity: 99.3% HPLC-verified, batch MT2-26070101
• Molecular Formula: C50H69N15O9 — Molecular Weight: 1024.18 g/mol
• Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
• Format: 10mg lyophilized powder, research use only
• Verified by: HPLC, mass spectrometry, peptide content, Karl Fischer water, endotoxin, and residual solvent testing

Research Applications

Melanotan II is a potent cyclic analog of alpha-melanocyte-stimulating hormone (α-MSH) researched for its agonist activity at melanocortin receptors, including MC1R, MC3R, and MC4R. Laboratory models use Melanotan II to investigate melanogenesis and pigmentation pathways, energy homeostasis and appetite regulation, and broader melanocortin receptor pharmacology. Our 99.3% pure batch with complete analytical documentation supports reproducible results across these research domains.

Certificate of Analysis (COA) — Batch MT2-26070101

Every batch of Melanotan II from Renew Labs is independently verified through a comprehensive analytical panel. Below is a summary of the results for this batch:

• Product: Melanotan II Acetate — CAS No.: 121062-08-6 — Product No.: MT210
• Molecular Formula: C50H69N15O9 — Molecular Weight: 1024.18 g/mol — Net Content: 10mg
• Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
• Appearance: White powder — Spec: White to off-white powder — Result: PASS
• Solubility: Conforms — Spec: Soluble in H2O / dilute acetic acid — Result: PASS
• HPLC Purity: 99.3% — Spec: NLT 98.0% — Result: PASS
• Mass Spectrum (ESI): 1024.2 — Spec: 1024.2 ± 1.5 — Result: PASS
• Peptide Content: 89.7% — Spec: NLT 80.0% — Result: PASS
• Water Content (KF): 3.9% — Spec: NMT 8.0% — Result: PASS
• Bacterial Endotoxins: Conforms — Spec: NMT 10 EU/mg — Result: PASS
• Residual Solvents: Conforms — Spec: Meets ICH Q3C — Result: PASS

Batch No.: MT2-26070101 | Mfg Date: Jul 01, 2026 | Retest Date: Jul 01, 2028 | Storage Conditions: Short term 2-8°C, long term below -10°C, protected from light & moisture.

Purity & Verification

This batch of Melanotan II is verified at 99.3% HPLC purity, exceeding the NLT 98.0% requirement. Full analytical verification includes HPLC, mass spectrometry, peptide content analysis, Karl Fischer water testing, bacterial endotoxin testing, and residual solvents testing, ensuring reliable, reproducible results for research applications.

Peptide Research & Literature

Melanotan II's melanocortin receptor pharmacology has been documented in the peer-reviewed literature for several decades. The following published sources may be useful background reading on its receptor activity, human pilot-study data, and reported adverse events:

• Dorr RT, et al. Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study. Life Sciences, 1996. PMID: 8637402.
• Wessells H, et al. Melanocortin receptor agonists, penile erection, and sexual motivation: human studies with Melanotan II. International Journal of Impotence Research, 2000. PMID: 11035391.
• Peters B, et al. Melanotan II: a possible cause of renal infarction: review of the literature and case report. CEN Case Reports, 2020. PMID: 31953620.

These citations are provided for scientific reference only. Kynetide's Melanotan II is manufactured and supplied strictly for laboratory and in vitro research use, and is not intended for human administration.

Frequently Asked Questions

What is Melanotan II studied for?
Melanotan II is studied for its agonist activity at melanocortin receptors (MC1R, MC3R, MC4R) in laboratory research into pigmentation, melanogenesis, and energy homeostasis models.

What is the CAS number and molecular formula of Melanotan II?
Melanotan II (Melanotan II Acetate) has CAS No. 121062-08-6 and molecular formula C50H69N15O9, with a molecular weight of 1024.18 g/mol.

What purity is offered?
This batch is verified at 99.3% HPLC purity, exceeding the NLT 98.0% specification, with full third-party Certificate of Analysis documentation.

How should Melanotan II be stored?
Short term storage at 2-8°C, long term storage below -10°C, protected from light and moisture, is recommended to preserve peptide stability for research use.

Is this for human use?
No. This product is strictly for laboratory and research use only and is not intended for human consumption.

How is Melanotan II supplied and shipped?
Melanotan II is supplied as a sealed, lyophilized powder vial and shipped with the batch-specific Certificate of Analysis included.

What documentation comes with each order?
Each order includes a full third-party Certificate of Analysis confirming HPLC purity, mass spectrometry identity, peptide content, water content, endotoxin, and residual solvent results for that specific batch.

Does Melanotan II require reconstitution before laboratory use?
As a lyophilized powder, Melanotan II is typically reconstituted with an appropriate solvent, such as bacteriostatic water, by qualified researchers prior to use in laboratory assays.

Is this the same compound referenced in the published pharmacology literature?
Yes. Melanotan II (Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2) is the same cyclic α-MSH analog studied in the melanocortin receptor literature cited above.

For laboratory and research use only. Not for human consumption. This product is not a drug, supplement, food, or cosmetic and is not intended to diagnose, treat, cure, or prevent any disease.