KPV 10mg

KPV 10mg is a research-grade Lys-Pro-Val tripeptide (the C-terminal fragment of alpha-MSH, positions 11-13) supplied for laboratory study of inflammation and gut-barrier biology. Every batch is HPLC-tested and ships with a batch-specific third-party Certificate of Analysis (COA) confirming identity and 99%+ purity. For laboratory and research use only. Not for human consumption. This product is not a drug, supplement, food, or cosmetic and is not intended to diagnose, treat, cure, or prevent any disease.

Research Applications

KPV is the C-terminal tripeptide fragment of alpha-melanocyte-stimulating hormone (α-MSH 11-13). It is studied in vitro and in preclinical models for anti-inflammatory activity, including NF-κB pathway modulation and PepT1-mediated transport, and is a common reference compound in intestinal-inflammation, gut-barrier, and skin research.

Purity & Verification

Molecular formula C16H30N4O4; molecular weight ~342.4 g/mol; CAS 67727-97-3; sequence Lys-Pro-Val. Every lot is analyzed by reversed-phase HPLC and mass spectrometry to confirm identity and 99%+ purity (this batch: 99.5%). A batch-specific, third-party COA is included in the product gallery so researchers can confirm purity and identity before use. Supplied as a white lyophilized powder soluble in H2O / saline; store sealed, cool, dry, and protected from light, and reconstitute per standard laboratory handling. Fast, tracked shipping from within the United States.

Peptide Research & Literature

KPV has been characterized in peer-reviewed literature on melanocortin-derived anti-inflammatory signaling and PepT1 transport. Selected published literature includes:

• Dalmasso G, et al. "PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation." Gastroenterology, 2008. PMID: 18061177
• Kannengiesser K, et al. "Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel disease." Inflamm Bowel Dis, 2008. PMID: 18092346

Frequently Asked Questions

How is KPV supplied and stored?
It ships as a white lyophilized powder in a sealed vial. Store refrigerated (2-8 °C) short-term and below -10 °C long-term, protected from light and moisture, per the COA.

What is it soluble in?
Per the batch COA, KPV conforms as soluble in H2O / saline for standard laboratory reconstitution.

Do you provide a Certificate of Analysis?
Yes - a batch-specific, third-party COA (HPLC purity, mass spec, endotoxin, residual solvents) is in the product gallery and matches the batch number on your vial.

Is this product for human use?
No. KPV is sold strictly for laboratory and research use only. It is not for human or animal consumption.